Nonfatal complications such as respiratory and renal, were seen in more than 50% of patients when more than 5 units were transfused. However, it was associated with high mortality as compared to patients without transfusion.
American College of Surgeons National Surgical Quality Improvement Program database over 3 years revealed very low incidence of massive transfusion. Timely recognition and efficient management are vital for successful outcomes after major blood loss. Massive blood loss is encountered in various situations like polytrauma, major surgeries, gastrointestinal bleeds, obstetric haemorrhage, etc.
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